PUBLICATIONS LIST


  1. Zlota, A. A., Bakale, R. P., Saranteas, K. E. ”Development of a robust scaleable process for the pilot plant manufacture of (S)-amlodipine-L-malate”, Organic Process Research and Development, in preparation.
  1. Zlota, A. A. “Chemical reactor mapping for safe and rapid scaleup”, Chemical Engineering Progress, in preparation.
  1. Zlota, A. A. “Still Crossing the Chasm: Chemical engineering modeling in drug discovery and development”, invited presentation at the 17th European Symposium on Computer Assisted Process Engineering”, Bucharest (Romania), 2007.
  1. “Highlights from the Literature: Some Items of Interest to Process R&D Chemists and Engineers”, Organic Process Research and Development, regular contributor.
  1. Zlota, A. A. “Chemical process scale-up tools: mixing calculations, statistical design of experiments, and automated laboratory reactors”, book chapter in: “Drug Discovery and Development”, Chorghade, M. S. (Ed.), John Wiley and Sons, in press.
  1. Zlota, A. A. “Understanding chemical reactor performance for successful scale-up and technology transfer”, invited presentation at the 10th Annual Technology Transfer Conference of the Institute for International Research, Orlando, Florida, 2006.
  1. Laughlin, S. M., Wilkinson, S. W., Bakale, R.P, Zlota, A. A. “(S)-amlodipine-malate”, US Patent application, 20060035940.

  1. Zlota, A. A. “Challenges in crystallization process scale-up”, invited presentation at the 6th Annual Polymorphism and Crystallization Conference of the International Quality and Productivity Center, San Diego, California, 2006.

  1. Senanayake, C. H., Tanoury, G. J., Wilkinson, S. W., Bakale, R. P., Zlota, A. A. “Method of resolving amlodipine racemate”, US Patent # 6,822,099 (2004).
  1. Zlota, A. A. “Chemical process scale-up using the RC1 ™ and VisiMix ™ scale-up calculations: the Bourne III case”, invited presentation at the 12th Mettler Reaction Engineering User Forum, 2004.
  1. Zlota. A. A. “Tools for rapid scale-up of crystallization processes”, presentation at the National Meeting of the American Institute of Chemical Engineers, San Francisco, 2003.
  1. Zlota, A. A. “Crystallization investigations using the RC1 ™, with VisiMix ™ and JMP ™”, invited presentation at the 10th Mettler Reaction Engineering User Forum, 2002.
  1. Zlota, A. A. “Using VisiMix TM to bridge between Lasentec TM protocols and the use of the FBRM probe in LabMAX TM and RC1 TM reactors”, invited lecture at the 2001 Lasentec TM User Forum.
  1. Zlota, A. A. “Towards a guide for the perplexed VisiMix TM user; successes and challenges in scale-up”, invited lecture at the First North American VisiMix TM Users’ Forum, 1999.
  1. Zlota, A. A. “Synergistic use of the RC1 TM, ReactIR TM and VisiMix TM for the safe and rapid scale-up of an exothermic heterogeneous chemical process”, Midwestern Pharmaceutical Chemical Process Consortium, 1996.
  1. Streib, W. E.; Zlota, A. A.; Caulton, K. G. “Molecular Structure of Cp*RuCl(PtBu2Me), Bull. Polish Acad. Sciences, 1994, 42 (2), 197, invited paper.
  1. Zlota, A. A.; Tilset, M.; Caulton, K. G. “Attempted oxidative generation of a dihydrogen complex”, Inorg. Chem. 1993, 32, 3816.
  1. Tilset, M.; Zlota, A. A.; Folting, K.; Caulton, K. G. “A loss of innocence? Charge-transfer interactions with Ph3PNPPh3 + as electron acceptor”, J. Am. Chem. Soc. 1993, 115, 4113.
  1. Calhorda, M. J.; Galvao, A. M.; Unaleroglu, C.; Zlota, A. A.; Frolow, F.; Milstein, D. “Rhodaoxetane: synthesis, structure and theoretical evaluation”, Organometallics, 1993, 12, 3316.
  1. Zlota, A. A.; Frolow, F.; Milstein, D. “Synthesis and X-ray structure of a simple metallaoxetane. Metal-based selectivity in oxidative addition”, J. Am. Chem. Soc. 1990, 112, 6411.
  1. Zlota, A. A.; Frolow, F.; Milstein, D. “Formation of iridialactones by CH2-O oxidative addition of propiolactone to Iridium(I)”, Organometallics, 1990, 9, 1300.
  1. Zlota, A. A.; Frolow, F.; Milstein, D. “Oxidative addition of Si-Cl bonds to electron-rich Ir I complexes”, J. Chem. Soc., Chem. Commun., 1989, 1826.
  1. Ashkenazi, P.; Weinberg, O.; Zlota, A. A.; Ginsburg, D. “Propellanes. Part LXXXIV. Reduction of [20.3.3]propellane-24,27-dione: the three isomeric [20.3.3]propellane-24,27-diols” , Recl. Trav. Chim. Pays-Bas, 1986, 105, 254.
  1. Zlota, A. A.; Ashkenazi, P.; Kapon, M.; Ginsburg, D. “Propellanes. LXXXVIII. Hydroxylation of 11,13-dioxo-12-methyl-12-aza[4.3.3]propella-3,8-diene with Osmium tetroxide”, Tetrahedron, 1986, 42 (12), 3199.
  1. Balaban, A. T.; Bota, A.; Zlota, A. A. “1,1-Bis[2-furyl]ethanes from 1-(2-furyl)-ethanols”, Synthesis, 1980, 136.



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